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Most treatment claims for MOTS-C still come from cell and animal studies

Rapid in vivo measurement of the topography of human skin by active image triangulation using a digital micromirror device

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Further Nrf2 translocates into the nucleus, heterodimerizes with one of the small musculo-aponeurotic fibrosarcoma (sMaf) proteins, binds to the antioxidant responsive element (ARE) or electrophile responsive element (EpRE) and promotes the transcription of genes encoding defense proteins/enzymes (Yamamoto et al., 2018)