Clinical considerations: All three products carry a boxed warning regarding the risk of thyroid C-cell tumors observed in rodent studies, contraindicating their use in patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
Some of the most common reasons include: Cost: GLP-1 drugs can run over $1,300 a month, and theyre not always covered by insurance
Whiteside EJ, Boucaut KJ, Teh A, Garcia-Aragon J, Harvey MB, Herington AC
The counter-argument is that a second receptor pathway is a second source of variability in effect, in tolerability, and in long-term safety questions
10.1016/j.rasd.2010.04.010
It complements dietary tweaks by supporting metabolic efficiencies, which could amplify weight management efforts