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Direct answer: Yes, current data suggests it remains safe with proper monitoring

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Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia & pituitary tumors

Future studies will be required to test whether serotonin receptor blockade could be an effective strategy for PBH therapy, and to ascertain whether additional serotonin receptor subtypes also contribute in diverse tissues and cell types relevant to PBH, such as L cells, enterocytes, enterochromaffin cells, islets, liver, and brain (56, 63)

GLP-1 receptor agonist for blood sugar control, may support weight loss

Due to the slowing of the gastrointestinal tract caused by GLP-1 receptor agonists, some patients may experience stomach pains or constipation