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(19) measured cortisol levels and found no significant change and these results were replicated in a study by Moro et al

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While both are highly effective, they have key differences in how they work, their effectiveness, and their side effect profiles

Dahl D, Onishi Y, Norwood P et al (2022) Effect of subcutaneous tirzepatide vs placebo added to titrated Insulin glargine on glycemic control in patients with type 2 diabetes: the SURPASS-5 randomized clinical trial