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How they affect natural GLP-1: Because youre getting both the sleeve effect (faster emptying from losing the stretchy part of the stomach) AND the bypass effect (food landing directly in L-cell territory), these procedures create the most dramatic hormonal changes of any bariatric surgery
You should also consult a doctor in the following cases 7 : Before any planned surgery or procedure, as GLP-1 RAs may affect gastric emptying and fasting requirements