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Irani M, Merhi Z
This transient pattern is consistent across the entire GLP-1 receptor agonist class
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A subset of dedifferentiated -cells were at early stage to convert into -cell in LOsG-treated animals As a subset of FoxO1-deficient -cells adapts the -cell fate, resulting in hyperglucagonemia 22 , we determined pancreatic glucagon mRNA in LOsG-treated -cells, which were associated with low or absent FoxO1 expression
De exacte mechanismen worden nog onderzocht
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