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Wharton S, Davies M, Dicker D et al (2022) Managing the gastrointestinal side effects of GLP-1 receptor agonists in obesity: recommendations for clinical practice

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Some patients with certain variants may benefit from dose escalation earlier, while others may find success with modified lifestyle approaches or dual-compound therapies

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The concentration-response curves were then plotted using the total area under the curve during the time of measurement post ligand addition