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Our team has worked with research groups comparing metabolic outcomes across both routes, and the confounding variable is almost always adherence
While the data point to beneficial effects on structural brain development, further investigation is crucial to determine the long-term impact of L-carnitine status and supplementation on functional neuro-developmental outcomes, such as cognitive and motor abilities, in this vulnerable population
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We also performed mitochondrial morphology assessments in dispersed islet cells from mice transfected with Control versus SPHKAP siRNA, which responded similarly to intact islets in terms of increased mitochondrial fragmentation following exendin-4 exposure in control conditions, but showed disturbed mitochondrial morphology under vehicle conditions and no further effect of exendin-4 exposure in SPHKAP siRNA-treated cells (Fig
Diabetol Metab Syndr 6:80
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