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The widely repeated claim that Dihexa is "seven orders of magnitude more potent than BDNF" originates from that flagged McCoy paper and reflects an assay-specific in-vitro spine-density measurement picomolar Dihexa versus nanomolar BDNF in one assay not a millions-fold advantage in a living brain
Enhances the brains ability to acquire new information and skills by promoting neuroplasticity, increasing dendritic spine density, and optimizing neural network efficiency for accelerated learning
Additionally, conserved-209 CEBP-ATF response element has a limited impact on regulating human ChaC1 transcription (48,53)
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