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For women with vitamin B12 below 358.7 pg/mL, we infer supplementation could improve pregnancy outcomes by restoring homocysteine homeostasis and enhancing oocyte quality, consistent with randomized trials showing that combined B12 and folate supplementation reduces oxidative stress and supports embryo development [7, 8]
No head-to-head comparison studies exist
10.1007/s00125-017-4330-3 39
Appeal, especially if you have comorbidities
glutathione plays a key role in most of these antioxidant mechanisms
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