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Journal of Medicinal Chemistry (2017) Kraus D, et al
Green R, Allen LH, Bjrke-Monsen AL, Brito A, Guant JL, Miller JW, et al Vitamin B12 deficiency Nat Rev Dis Primers
Six controlled trials in approximately 900 participants are summarized in Stier et al
Ozempic is approved to treat type 2 diabetes Wegovy is specifically approved for chronic weight management In some cases, providers may prescribe Ozempic off-label for weight management when appropriate, but Wegovy is the formulation designed and approved for weight loss
Tesamorelin has shown some mild-to-moderate side effects
One study found that high doses of oral B12 (1,000 mcg daily) could provide adequate absorption even in the presence of intrinsic factor deficiency
