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For transdermal botanical delivery specifically, published interest in this delivery route exists for compounds with oral bioavailability challenges
Neuroprotection research includes hippocampal ischemia-reperfusion models in rats (PMID 32558293) and investigations into the brain-gut axis as a candidate explanatory framework for the broad effects observed across tissue types (PMID 27138887)
In addition, studies have shown that Fenugreek can help reduce symptoms of PCOS, vaginal dryness, irritability, and mood swings
On the other hand, it causes inflammation and skin irritation, but milder temperatures reduce the base level of inflammation and calm the skin
Kentucky, USA
Nafee, N., Forier, K., Braeckmans, K
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