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Abbreviations BAT: Brown adipose tissue CEX: C-terminal extension CNS: Central nervous system DIO: Diet-induced obese DPP-IV: Dipeptidylpeptidase-IV EMA: European Medicines Agency FDA: Food and Drug Administration GcgR: Glucagon receptor GIP: Glucose-dependent insulinotropic polypeptide GIPR: GIP receptor GLP-1: Glucagon-like peptide 1 GLP-1R: GLP-1 receptor OXM: Oxyntomodulin PEG: Polyethylene glycol STZ: Streptozotocin T 3 : Thyroid hormone References Obesity and overweight fact sheet

A large study of privately insured adults and Medicare beneficiaries published in JAMA Network Open showed that annual health spending increased by $326 per person for each percentage-point increase in body mass index (BMI) when obesity was left untreated

Liu Y, Jiao C, Zhang T, Li X, Li P, Lu M, et al

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