B12 deficiency leads to a methyl-trap where folate is trapped as 5-MTHF, reducing methionine synthesis and increasing homocysteine
Importantly, semaglutide carries a boxed warning for risk of thyroid C-cell tumors and is contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)
Many people taking GLP-1 medications notice changes in appetite, taste, and food preferences
Isotonic formulations minimize the risk of irritation, dryness, or swelling of the nasal mucosa and promote better patient adherence
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Compounded semaglutide has never been tested in clinical trials, so we can't say for certain whether it works