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And in 2021, the results from a series of five STEP trials (Semaglutide Treatment Effect in People with obesity) demonstrated marked weight loss even in individuals without type 2 diabetes (T2DM): Phase 3, for example, showed an average loss of about 15 percent over 68 weeks, more than double achieved by any prior obesity drug

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The same analysis did not find a significant reduction in overall blood clot or DVT risk, which is why your vein doctor's full picture of your health still matters when assessing your individual risk

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Safe use of GLP-1 therapy hinges on close medical supervision and frequent kidney function tests