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doi: 10.1007/s10637-011-9763-9 148 CarvajalRDLawrenceDPWeberJSGajewskiTFGonzalezRLutzkyJet al

The relationship between half-life and dose range is not arbitrary

39 Similarly, lutein plus zeaxanthin, at doses of 10 mg and 2 mg, respectively, improved tests of memory, reasoning, and complex attention after one year in a placebo-controlled trial with 51 healthy subjects aged 1830 years

Diabetes Care, 2015

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If this occurs: Allow additional time at room temperature (up to 30 minutes total) Very brief, gentle vortexing (35 seconds) as a last resort If aggregation persists, consider re-solubilizing in 10 mM HCl at a slightly lower concentration 6