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More severe side effects are rare but can include low potassium, headache, dizziness, and chest pain

[10] The medication is primarily eliminated through proteolytic degradation

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In mouse models of highfat dietinduced obesity, it treatment significantly reduced mRNA and protein expression of TNF, IL6, and other inflammatory factors in adipose tissue and decreased macrophage infiltration - a hallmark of adipose inflammation

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In addition, the ketogenic diet has a better response when used as an additional treatment along with antiseizure medications [111]