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We evaluated patient-specific, IBS-related and agent-specific factors and found substantial heterogeneity in real-world practice
This is because injectable drugs do not encounter barriers like the gastrointestinal tract and are rapidly absorbed into the bloodstream
Why Does Study Design Matter for Evidence Weighting
In addition to providing alternative fuels for energy production, enhancing insulin sensitivity and boosting brain glucose metabolism are both high priority therapeutic targets for neurodegenerative disease
Free radical biology & medicine 42 , 14701480, doi: 10.1016/j.freeradbiomed.2007.01.044 (2007)
Depending on the clinical indication, doses range from 2.5 mg to 15 mg, with gradual dose escalation recommended to improve treatment tolerability
