These effects were generally dose-dependent, most pronounced during dose escalation, and are consistent with the known side effect profile of approved GLP-1 receptor agonists
This timing requirement is specified in the SmPC and is essential for proper absorption
Yet the soaring enthusiasm for so-called glucagon-like peptide-1 receptor agonists, first approved in 2005 , overshadows an array of risks related to their off-label use
In the SURMOUNT-1 trial, participants taking Mounjaro showed significant improvements across several mental health measures, including emotional functioning, social interactions, and overall psychological wellbeing, compared to those taking a placebo
It is not yet FDA-approved, but phase 2 trial data give a detailed picture of its side effect profile
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