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Among participants who had prediabetes at the start of the study: 71.1% achieved normal blood glucose by week 64 in the semaglutide group Compared to just 33.3% in the placebo group That's a striking reversal rate for prediabetes a condition affecting more than 88 million U.S

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,[21] is more stable in blood plasma than GSH, and enters the cells directly, where it is converted to reduced glutathione by the abundant cytoplasm thioesterases

Both compounds were freshly dissolved in vehicle (PBS with 0.1% BSA)

FIGURE 5 Crucially, this peripheral dysregulation was mirrored in the brain

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