No participants withdrew from any trial due to tolerability issues, indicating that even when side effects occurred, they were sufficiently manageable that participants chose to continue treatment
The study did not determine the reason patients were prescribed these medications and the severity of the strokes that patients experienced could not be assessed, which may have affected the outcomes
Here's What That Might Mean Medically reviewed by Oghenefejiro Okifo | MD , Harvard Medical School | Henry Ford Hospital - Detroit, MI on August 18th, 2025
00:12:26 Craig Williams Yeah, Ill add, Sara, that as far as being concerned that the drug itself has like neurologic causes or toxicities, I also have not appreciated that
Methylcobalamin, vitamin B12 preparations containing benzyl alcohol should be avoided in premature neonates because benzyl alcohol has been associated with gasping syndrome, a potentially fatal condition characterized by metabolic acidosis and CNS, respiratory, circulatory, and renal dysfunction
However, the current techniques for isolating and purifying exosomes frequently do not scale well and can lead to poor yields and heterogeneity