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Furthermore, TGF-1 induced neurogenesis-associated genes such as the bHLH transcription factor acheate-scute complex homolog-like 1 ( Mash1 ), the Notch pathway gene HES1 , the Notch ligands delta-like 1 ( dll1 ) and jagged1 ( Jag1 ), the stem and progenitor cells marker Nestin
Individual results vary significantly between patients
Research indicates that ARDS patients exist in two distinct molecular phenotypes: hyper-inflammatory and hypo-inflammatory, with significant differences in therapeutic response (130)
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