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This ensures accurate dosing and avoids errors

Increases cellular NAD and SAM availability and lowers intracellular 1-MNA, consistent with enhanced NAD salvage and a favorable methyl economy [13]

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Finally, although the correlations between the metabolome and microbiome were established using robust statistical analyses, there was limited statistical power and there are also limitations to the statistical approaches used herein (e.g., log transformation to resolve non-normal distribution and/or heteroscedasticity 103 )