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These participants were randomized to once-weekly subcutaneous retatrutide (1, 4, 8, or 12 mg) or placebo for 48 weeks
Diarrhea affecting 12 to 20 percent of users, typically most prominent during the first two to four weeks of treatment or after dose increases
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The relationship between muscle mass and muscle strength in the elderly
Highlights include durable improvements in endogenous insulin secretion and glycemic control across both type 1 and type 2 diabetes, along with translational data showing activation of pathways associated with fat reduction and lean mass preservation
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