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Conclusion: Sublingual and oral B12 supplementation appear to be as effective as intramuscular (IM) injections in improving cobalamin status and reducing homocysteine levels

Gastrointestinal applications show particular promise given the peptides origin, with documented repair of mucosal damage, restoration of tight junction integrity, and protection against NSAID-induced ulcers

Here is a revised and more accurate explanation of the reasons a UK GP surgery might refuse to give a B12 injection a day earlier than scheduled, incorporating the points youve raised and providing a more scientifically grounded perspective: 1

Proper handling and storage of bacteriostatic water directly determine whether the 28-day in-use window delivers reliable results

Further evidence also states that stable gastric pentadecapeptide BPC 157 is an anti-ulcer peptidergic agent, proven in clinical trials to be both safe in inflammatory bowel disease and wound healing, stable in human gastric juice, with no toxicity being reported [12]

Their combined effects enhance the regeneration of soft tissue and may improve the overall healing process