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A notice on the FBI's website warns that the fraudulent drugs purporting to contain semaglutide have been found instead to contain "compounded mixtures of unknown drugs that do not contain semaglutide, drugs with high levels of impurities, and unsafe or unapproved drugs." The health risks of taking the "misrepresented drugs" include everything from cardiac and gastrointestinal disorders to nervous system disorders, psychiatric disorders and death, according to the FBI

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The drug works as a dual GLP-1/GIP receptor agonist, targeting hormones involved in appetite regulation, insulin secretion, and energy balance

- [Once-Weekly Semaglutide in Adults with Overweight or Obesity (STEP 1)]( *New England Journal of Medicine*, 2021

Therefore, the R-isomer of ALA is believed to be the form that exerts most of the biologic effects of ALA