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coli over-expression vectors have fusion tags, the translational initiation site, the 5 untranslated region (5 UTR), the antibiotic selection marker, the transcription promoter site, and the origin of replication, just like any other expression vector

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It is now approved as afamelanotide in both the United States and Europe to prevent sun-related skin damage in patients with erythropoietic protoporphyria

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This means every vial has been compounded under pharmaceutical-grade conditions, tested for sterility and potency, prepared specifically for human administration under a valid prescription, and tracked from source to patient