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Macrophages of the vascular wall can collect iron, and iron overload in turn causes macrophages to transition to an anti-inflammatory phenotype, which leads to inflammation, oxidative stress, and increased plaque formation
It is part of long-term treatment for obesity, metabolic disease, insulin resistance, and related conditions
Diet-induced insulin resistance impairs hippocampal synaptic plasticity and cognition in middle-aged rats
Materials and methods: Multicenter randomized controlled trial across Denmark with 277 women with recent GDM randomly allocated in a 2:1 ratio to intervention group (n=184) or usual care group (n=93) at 10-14 weeks after delivery
Xiong Y, Mahmood A, Meng Y, et al
(PubMed) Levy MM, Fink MP, Marshall JC, et al
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