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Discontinuation in trials: retatrutide trial discontinuation due to adverse events was 6-10% across the higher-dose arms meaningful but lower than the dose-related side-effect profile would suggest, which indicates most participants tolerated the protocol

Signs of an allergic reaction can include itchiness, a rash, hives, chest tightness, shortness of breath and swelling of the throat, lips, mouth or tongue

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"FOXO4-DRI improves spermatogenesis in aged mice through reducing senescence-associated secretory phenotype secretion from Leydig cells"

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