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2 1 JDMM BMI200320152015BMI25BMI22 303402 GLP-12GLP-1GLP-1 GLP-1111GLP-1 GLP-1 GLP-12 GLP-1 GLP-1 2GLP-1 GLP-1 210GLP-14GLP-1 GLP-1 2393GLP-14 GLP-1GLP-1DPP-4 :LiraglutideDPP-42 3827(5,032)129(2,091)24HbA1cHbA1c 0.9mg:LiraglutideDPP-4(:Vildagliptin:Sitagliptin:Linagliptin:Alogliptin:Teneligliptin:Trelagliptin:Omarigliptin) 2:Liraglutide0.9mgDPP-4 1HbA1c7% GLP-1HbA1c1HbA1c7.0%CCPI,100C/HbA1c7.0%SU1.861.10 GLP-1 GLP-1 GLP-1GLP-1GLP-1 BMI 25kg/m257 150mg/dL2200mg/dL0.3mg/10.3mg/0.9mg/ GLP-1 GLP-12 GLP-1212GLP-1371.59kg GLP-1 GLP-1 GLP-1LEADERSUSTAIN-6 24 24 14GLP-1DPP4GLP-1GLP-1GLP-1 GLP-14 2 SU10 UKPDS24,209 SU2,729met3421,13810 Holman RR et al.N Engl J Med 359(15)1577-1589, 2008 21013159242 50% GLP-130 GLP-1 23HbA1c7%1,168 HbA1c7%6Hb1Ac7% Pantalone KM, et al

Patient researchers often achieve better long-term outcomes than those who push too hard too fast

Direct comparison with bariatric surgery in models

GLP-1-exposed pregnancies were also at a higher risk for: gestational diabetes (RR = 1.3

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they reflect the growing scientific interest in lupin as a functional food