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In addition, a previous study showed that C cells in human thyroid tissue do not express GLP- 1R [23]
To conclude, although the use of model cell lines is now being superseded by more sophisticated models such as ex vivo cell cultures and organoids, model cell lines remain a low cost and fast alternative to screen the impact of drugs on a wide range of endocrine cells under buffer conditions that may not be well tolerated by ex vivo models and organoids
Structural changes in collagen and elastin networks require sustained signaling to manifest fully
Goderie T, van Wier MF, Lissenberg-Witte BI, Merkus P, Smits C, Leemans CR, Kramer SE
Clinical research has examined neuropathic symptoms and small-fiber nerve measures in selected patient populations
