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It is essential to emphasise that these remain investigational applications, and patients should not alter prescribed treatments without medical supervision

However, native amylin presents significant challenges for therapeutic use, including rapid enzymatic degradation, tendency to form pathological amyloid fibrils, and poor bioavailability when administered exogenously

However, the causative relationship among them remains unclear

It is commonly researched for its role in melanin production, skin pigmentation mechanisms, and melanocortin receptor activity in laboratory settings

Li Y, Zhang H

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