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Genetic testing is also available for breeds that are prone to inherited selective cobalamin malabsorption

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Athletes and individuals who exercise daily may have low B12 levels, due to the increased metabolism

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PMID 13374343

Specifically, eligible studies included participants (P) with a confirmed diagnosis of vitamin B12 deficiency, interventions (I) involving oral or sublingual vitamin B12 administration, comparators (C) using intramuscular supplementation, and outcomes (O) reporting changes in serum vitamin B12 or homocysteine levels