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Among these RTAs, the strategy that has recently attracted the greatest interest, particularly in the context of cancer, is targeting the enzymes that regulate the ubiquinol (CoQ 10 H 2 , reduced) pool to sensitize cancer cells to ferroptosis

Although the context-dependent, bidirectional modulation of ferroptosis by Kla presents promising therapeutic avenues, notable barriers remain between current mechanistic insights and clinical implementation

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For a discrete injury like rotator cuff tendinitis, this targeted approach makes pharmacological sense

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