& Sullivan, S
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These are called social determinants of health and require policy-level interventions
Yamamoto BJ, Elias PD, Masino JA, Hudson BD, McCoy AT, et al
This point is effectively made in a recently conducted large trial, which states that, our understanding of the mechanisms of cardiovascular protection with [the GLP-1 agonist] semaglutide remains speculativeclinical benefit is [thought to be] achieved through multiple interrelated pathways. Acknowledgement of this evidence gap prompted our lab, through use of a large animal model of CAD that replicates the features of disease as it occurs in humans, to investigate the cardiac consequences of semaglutide administration
The duration mismatch is the whole story