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I look at epidemiological studies, mechanistic studies, and clinical trials to form the most complete picture possible about a given topic
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For inflammatory cascades, curcumin inhibits NF-B nuclear translocation (Zinatizadeh et al., 2021) and blocks MAPK phosphorylation (Lee et al., 2020), significantly reducing the release of inflammatory mediators like TNF- and IL-6
26,27 Its mechanism is similar to that of other GLP-1 receptor agonists