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Weight-bearing exercise invokes Wolff's Law, the principle that bone responds to mechanical stress by becoming denser and stronger
Kovacs-Nolan J, Rupa P, Matsui T, et al
377 Epithelial cells thus lose their intercellular adhesion capacity and acquire mesenchymal properties
They also support wound healing and protect against oxidative damage
This re-analysis yielded much better predictions (adjusted R 2 from 0.28 to 0.75), and all of the results were significant (p-values from 0.02 to 0.0006)
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