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Statistical software All analyses were performed using R 4.1.0 (The R Core Team & The R Foundation for Statistical Computing, Vienna, Austria) in the integrated development environment (IDE) RStudio 1.4.1106 (RStudio, PBC, Boston, MA, USA)
Research usually starts at the lower end for both, and doses are increased gradually as the models response and tolerance are observed
These symptoms may improve over time for some people, especially with gradual dose adjustments and smaller, balanced meals
doi: 10.1371/journal.pone.0132017 109 SalkerMSSinghYDurairajRRPYanJAlauddinMZengNet al
Ozkan S, Jindal S, Greenseid K, Shu J, Zeitlian G, Hickmon C, et al
NICE recommends treatment only within specialist weight management services, typically for a maximum of 2 years, and only if non-surgical weight management interventions have been unsuccessful
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