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Methods Animal experiments The humanized Townes SCD transgenic (B6;129- Hba tm1(HBA)Tow Hbb tm2(HBG1,HBB*)Tow / Hbb tm3(HBG1,HBB)Tow /J) mouse 65 was obtained from Jackson Laboratories ( as breeders
GagginiMCarliFRossoCBuzzigoliEMariettiMDella LattaVet al
Lin Y, Wang K, Ma C, Wang X, Gong Z, Zhang R, et al
doi: 10.4081/MONALDI.2021.1981 239 KocHCXiaoJLiuWLiYChenG
Concomitant deficiencies (iron, folate), chronic illness, or drug interactions may blunt clinical response and warrant further evaluation
The proposed advantage is that some glutathione may be absorbed through oral tissues rather than depending entirely on the gastrointestinal tract
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