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Large-scale, randomized controlled trials are critically needed to establish definitive efficacy for specific clinical indications and to compare these peptides with established therapies

Human safety information remains limited, and potential risks may not be fully understood

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Focusing on providing the 'raw materials' (cysteine, glycine) and cofactors (B vitamins, selenium) is the most effective and sustainable strategy for supporting endogenous production

Information specific to people with Down syndrome is included below