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It is not a passive fat burner and produces little without the exercise that actually moves fatty acids into the mitochondria for oxidation

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Compared to fission, mitochondrial fusion is regulated by mitochondrial fusion proteins 1/2 (Mfn1/2) and optic atrophy 1 (OPA1), which control the fusion of the inner mitochondrial membrane (IMM) and outer mitochondrial membrane (OMM), respectively (50)

Nicotinamide riboside (NR) has novel food authorisation and is legally sold as a food supplement in the UK