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When administered as a once-weekly subcutaneous injection, semaglutide has a half-life of approximately one week, reaching steady-state concentrations after 4-5 weeks

While both B12 shots and oral supplements can raise your vitamin B12 levels, injections offer some key advantagesespecially for weight-loss patients who need a quick energy boost for workouts and metabolism support: Superior absorption: B12 shots bypass the digestive tract entirely, delivering 100% of the dose directly into your muscle

10.1007/s00239-004-2666-z 136 TorresM