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Theres no reason to completely change your diet in order to get a healthy dose of vitamin B12, says Taylor

After drawing up the sterile water and performing the reconstitution, promptly discard the empty vial or ampule and any remaining water

Avoid vigorous shaking

References 1 Nature Medicine (2014)Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity (preclinical)

Fasano A 1

In rare cases where B12 is essential but acne remains intractable, dermatologists may consider oral isotretinoin, which in the UK can only be initiated by consultant dermatologists and requires strict monitoring, including a pregnancy prevention programme for women of childbearing potential