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Oral melanotic macules An oral melanotic macule, by conventional definition is a focal, well-defined, uniformly coloured oral mucosal hyperpigmentation, less than 1 cm in diameter, of unknown aetiology
In the Phase 2 trial, starting at a lower dose (2 mg versus 4 mg) significantly reduced the incidence and severity of gastrointestinal adverse events without compromising weight-loss outcomes
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doi: 10.1111/dom.15058 46 YamadaYKatagiriHHamamotoYDeenadayalanSNavarriaANishijimaKet al