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For patients requiring additional control, a 2 mg weekly dose is also licensed in the UK after at least four weeks at the 1 mg dose

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The antibodies used for the immunoblot assays were: GCLC (Santa Cruz Biotech, #sc-390811), NQO1 (Sigma Prestige Antibodies, HPA007308), ACTIN (Sigma, A1978), NRF2 (Cell Signaling Technology, #12721), NRF1 (Cell Signaling Technology, #8052), YAP/TAZ (Cell Signaling, #8418) 4-HNE (Abcam, #ab46545) and Lamin A/C (Cell Signaling, #4777)

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Parkinson's disease symptoms are reduced

Next, we monitored autophagic flux in GSH-depleted cells by using a tandem fluorescent-tagged LC3 lentivirus mRFP-GFP-LC3 expression system