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Conditions such as gastroparesis (delayed gastric emptying), peptic ulcer disease , coeliac disease , hypothyroidism , or in rarer cases upper gastrointestinal malignancy can all present with early satiety or persistent fullness

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It is not a licensed medicinal product under the UK Human Medicines Regulations 2012, and no dosing or administration guidelines are provided in this guide or in any Ascend Peptides UK documentation

This concept represents an emerging paradigm that may extend beyond a passive luminal absorption to active glucose uptake from the circulation into intestinal epithelial cells and subsequent excretion into the lumen

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