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ICV IgG1-treated mice maintained stable body weight, while all doses of ICV mGIPR-Ab/P3 led to substantial weight loss (Extended Data Fig

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F.HorngA.NiethammerT.PagenstertI.SieversB.JanssonV.et al (2009)

Gejl et al

Subsequent investigations indicate that long-acting sustained-release pirfenidone did not enhance the clinical progression of septic AKI, however, it is safe and does not cause adverse effects [106]