This bibliography is provided for reader reference
Methods Peptide agonists and general reagents Rat amylin (rAmy), salmon calcitonin (sCT) and human calcitonin (hCT) were purchased from China Peptides
Your provider may also consider dose optimization, combination approaches, or ruling out underlying factors like thyroid dysfunction
Published Phase 2 studies lasted 12 or 24 weeks
For patients who need both Toujeo specifically (the U-300 concentration) and a GLP-1 agonist, separate injections are currently the only option, as there is no combination product using the U-300 concentration
Preclinical work also suggests amylin signalling interacts with mesolimbic dopaminergic pathways implicated in the hedonic, reward-driven component of eating a mechanism explored further in our overview of how cagrilintide influences brain satiety circuits and reward-driven eating