It helps regulate blood sugar by mimicking the hormone GLP-1, which stimulates insulin production and slows gastric emptying
Who can use GLP-1 agonists
Safety & Side Effects Most common side effects are mild and transient: Mild increase in heart rate Nausea Decreased appetite Constipation or diarrhoea Fatigue In many cases, mild side effects from the drug can be temporary
Studies have shown that semaglutide remains effective in managing blood sugar and supporting weight loss, even when women are also taking oral contraceptives
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Novo Nordisk reined in its growth forecasts for the year in its second-quarter financial results update, blaming "persistent use of compounded GLP-1s, slower-than-expected market expansion, and competition." Compounding of semaglutide should have come to a halt in the US since the drug was removed from the FDA list of medicines in short supply, but various companies continue to provide compounded GLP-1s under a loophole that allows the sale of 'personalised' formulations