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Notably, we recently demonstrated that HITI outperforms HDR in terms of knock-in efficacy for GFP gene at the Alb locus in mouse hepatocyte when using clinically relevant, lipid nanoparticle (LNP)-based deliver systems

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Nausea, constipation and delayed gastric emptying are common to GLP-1 agonists as a class and are not reduced by moving from injection to a sublingual formulation

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